Connections secured with TLS aren't effective if a) you can compromise the CA, b) have the private keys, c) have cooperation of the appropriate company (most likely), d) have compromised the server, e) are aware of flaws in the encryption algorithm, f) weak keys have been used, or g) have compromised the client computer.
Compromising the CA isn't as powerful as most would think. It does allow you to MITM, however it does not allow you to do so invisibly. Someone who is paying attention to the public key could notice that it changed.
