American McGee's Alice
Resident Evil
Perfect Dark
Old NES Games based on the Alien movies (Ripley)
Donkey Kong Country 3 (Diddy Kong is the main character)
Chrono Trigger's main hero is a male, but 3 of the other 6 playables are strong females (2 of the others are a Frog and a Robot)
There are definitely more games with male protagonists than female, but there are enough to list.
You meant Dixie.
http://www.giantbomb.com/female-protagonists/92-2287/
Ironically, the first games I thought of, Fallout and Elder Scrolls, are probably not the best choice for a girl who can't read yet.