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What’s a typical rate for infections per person-year among people not using these precautions? For those who don’t know follow the epidemiology here, how good effective are the older drugs compared to not taking them?

Having grown up when AIDS was peaking, the idea of this scourge preventable and treatable feels damn near like sci-fi, and I’m thrilled at the progress we’ve made.



This heavily heavily depends on the population you choose, given the difference in sexual habits.

As a data point, the paper below shows 1,213 out of 18,401 high-risk people in France got infected in 4 years (and 260 out of 31,992 with the previous gen prep, it seems this one reduces it by ~10x again)

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2...


Thanks for that! So yeah, by that, existing PrEP is very effective, and this new one is much better yet.

What a medical miracle, seriously!




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