If there is an actual set point theory I didn't learn about it from this article. What are the metabolic pathways that alter the set point? How do the recommendations affect those pathways? What actually is the set point? Is it one thing or many things? And surgery alters the set point, really? Isn't surgery a mechanical solution instead of a hormone altering solution? The set point theory seems more like an observation that the body acts like it has a set point rather than an actual theory about the biochemistry of the body. Does fasting alter the set point? Does food composition affect it? Does sugar affect it? To what degree does each type of exercise alter the set point? What raises the set point? If we have an initial set point why do we ever gain weight at all? Is the set point measurable? Do the drugs actually affect the set point or just temporarily fool it and how? If science has proven a set point exists why is science still doing research on methods to change behavior? If food makers have altered food to increase the set point is that not a major clue to what causes the set point to change and to what the set point is? There seems to be a lot of willful ignorance in the medical research on obesity, particularly research in behavior change. I've worked on some of it that I thought was absolutely useless.