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> looking at all of this literature together, of around one week of chronic sleep loss, it really does suggest that you injured the brain to some extent

I guess that is at least a fairly decent time to have persistent inadequate sleep. At least if this is happening to you regularly then you really do have a specific issue to address and routine type insomnia (2-3 nights of less than adequate sleep) are probably not figuring into it strongly. For effects of that type, I would have thought there were cohorts of people with chronically disrupted sleep (airline workers, shift workers etc) that could make good validation sets to look for such effects. If that hasn't been done yet I'd be surprised so I feel like the more likely answer is that whatever these effects are, they at least require a substantial protracted period of poor sleep.



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