I had the opportunity to ask a very social-justice-minded friend of mine how custom pronouns and genders could possibly work in Arabic, which has many deeply integrated rules on gender modification of words. Adjectives, verbs, and pronouns all change depending on the gender of the object. Her response was that the language must be changed to suit the preferences of people with nonstandard genders.

It really feels sometimes that this is a sort of soft English imperialism, forcing other languages to the margins by making their use "impolite" to the global audience.