It really depends on the game. Too many games rely on visuals as the primary form of output in a way that simply cannot be made particularly accessible, outside of the obvious things, which many newer games at least seem to address, to various extents, as shown in the GMTK: colorblind modes, large text[1], on-screen icons for sounds, no quick-time events or other twitch controls.
Having said that, I think The Last of Us 2 needs to be studied more as they appear to have done an amazing job with accessibility, given that a blind player was able to complete it. Maybe other developers can learn from that.
[1] And a personal pet peeve of mine: pixel art games using pixellated fonts. I find most pixel fonts extremely difficult to read. When I posted about that on r/gamedev once I just got yelled at because "artistic vision", but your artistic vision is useless if I can't play the game. At least give me the option to use a normal, crisp font.
Having said that, I think The Last of Us 2 needs to be studied more as they appear to have done an amazing job with accessibility, given that a blind player was able to complete it. Maybe other developers can learn from that.
[1] And a personal pet peeve of mine: pixel art games using pixellated fonts. I find most pixel fonts extremely difficult to read. When I posted about that on r/gamedev once I just got yelled at because "artistic vision", but your artistic vision is useless if I can't play the game. At least give me the option to use a normal, crisp font.