I'm not a classicist in fact. If you're Thelonius Monk go ahead and play, but in this same thread we have some people complaining of finger fatigue and cramps. That's something that a teacher can correct easily.
No, because the piano is not an ergonomic instrument. No matter what, you're going to experience finger fatigue and cramps. And that's even assuming you have a hand size that fits the one, standardized keyboard size.