> I take a prescribed ketamine lozenge every day. I don't experience any psychedelic effects and I'm fine with that.

Many of the researchers and clinics are gravitating toward ketamine regimens that avoid hallucinations entirely, like your current treatment regimen.

Ketamine has some inherent anti-depressant effects that don't depend on hallucinating. Unfortunately, many psychedelic proponents have tried to push the narrative in the opposite direction to emphasize the trip.

It's unrealistic to expect depressed people to routinely go on psychedelic trips to keep their depression at bay. It's also unrealistic to expect people to trip frequently and not have part of the population start to accumulate weird, irrational ideas from their trips.

A medicine that captures the anti-depressant effects without causing a psychedelic trip or really any cognitive distortions at all would be far better than expecting people to trip regularly. I don't understand the aversion to pharmaceutical companies pushing the research in this direction.

I’m very curious about how much you take daily and the effects. I’ve read about the super high dosage therapy, and that made a lot of sense to me. Are you just ever so slightly dissociated at all times?

Not the OP, but I'm prescribed ketamine for chronic nerve pain.

Prescription is for 25mg orally 4-6 times a day, but I find 15mg as effective as 25mg, but with no side effects at all.

At 25mg I do feel slightly dizzy for an hour or so.

Ketamine has a small, but noticeable effect on the pain - but has had a huge effect on my ability to deal with the pain.

I dunno about them but, but I get by on 20mg taken weekly. If I miss a dose, it's usually ok. If I miss two, suicidal ideation is my dominant thought pattern. As for effects, I'm a little dizzy for about 30 minutes and I prefer to spend this time napping or in a hot bath.