Tylenol is an odd choice of example here given that it poses a risk of liver damage and for some subsets of the population it's actively dangerous to take it. We literally lace some drugs with Tylenol to make them "abuse-deterrent" because we know taking too much of it would harm you.
caloric undernutrition
acute liver failure
liver problems
severe renal impairment
a condition where the body is unable to maintain adequate blood flow called shock
acetaminophen overdose
acute inflammation of the liver due to hepatitis C virus
Obviously doctors are experts and will make the right decision based on risks and advantages, but tylenol is a poor choice of example for 'effectively risk-free drug'. I've seen multiple people mention that their meds are laced with it even though it's contra-indicated for them
