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> ...Big Five neuroticism...

It's gonna be really hard to deconvolve hormones from environment. Men and women are treated very differently in our culture; men's and women's behaviors are interpreted very differently; the former having a possible causal relationship with neuroticism, the latter having a possible causal relationship with diagnosis. You'd need a fairly large study involving a large number of trans people who aren't on hrt but pass as well as those who are.



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