I think the real question here is whether the application should be loading the main content via AJAX in the first place. Tim argues here that it should not, for this use case.
Then that's what the article should say, instead of hating on the hashbang syntax, which is currently the best solution to the problem.
I also don't see why these web pages (specifically twitter) shouldn't be an ajax application - I think loading a page statically, and then the data via ajax is a Good Thing™.