I've tried to switch from Gnome to OS X several times over the years (we use mostly OS X in my office). I have always ended back up on Ubuntu (or Arch). Gnome just feels more intuitive, everything pretty much does what I would expect it to do. Also integrated package managers are a pretty killer feature that all Linux distros come with these days. Recently on my work machine I switched to XMonad and my productivity has seriously gone up thanks to it.