Edge is implementing (updated the roadmap), Firefox ships enabled WC's in closest release (it is already in the beta) I think Firefox 63 will ship in a week?.
what polyfills are you talking about? And no, Polymer is not a polyfill for custom element. Please link me to a library that will polyfill the entire shadow DOM and Custom Element spec so that I can write the same code without polyfills on platforms that support both specs and only load the polyfills on platforms that do not.
That leaves only IE11/Edge with polyfills.