If you're on Android, try a firewall-based system-wide adblocker like Blokada (https://blokada.org/index.html). It's very effective at blocking ads, including on mobile Chrome, and it's grandma-friendly (doesn't need root, nothing to maintain)
There is a "Brave" browser which is chrome with ad-blocker. But I prefer firefox on all mine devices because of syncing passwords, history and ability to send tabs from desktop to mobile devices.