The one thing Coda or any other GUI based editor is really nice for is CSS. While it's rare at I have to delve into that stuff, it is really nice to have amenities like a color picker and a visual representation of the colors instead of just a hex code. So while I use emacs for my source as well, I jump into Coda for the rare cases where I am making style changes.
I'd love if there was some emacs-y way of doing this, but it's just not good at gui tasks.
What a program.